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102 Alternatively, various groups are advocating for that incorporation of novel markers, such as a complex karyotype55 or epigenetic subsets, 27,28 into clinical practice. Every one of these novel prognostic and/or predictive products will must be validated in cohorts of people addressed with targeted brokers.

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one When this kind of inhabitants is detected in enlarged lymph nodes of sufferers without having peripheral lymphocytes, the time period small lymphocytic lymphoma (SLL) is made use of, indicating a medical variant of the same histopathological and molecular entity.two

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